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Azithromycin Dosage: What You Need to Know

Azithromycin is a popular antibiotic that doctors prescribe for everything from ear infections to sexually transmitted diseases. The biggest question people have is “how much should I take?” Below you’ll find the most common dosing plans, when to adjust them, and safety tips you can use right now.

Standard adult dosing

For most infections, adults start with a 500 mg tablet on day 1, then 250 mg once daily for the next four days. This five‑day schedule is what you’ll see on the label for conditions like bronchitis, sinusitis, and certain skin infections.

If you’re treating a more severe infection—like certain sexually transmitted infections—the doctor may order a single 1 g (1000 mg) dose. That’s a one‑time pill, no follow‑up doses needed.

When it comes to timing, azithromycin can be taken with or without food. Some people find that a light snack helps prevent mild stomach upset, but it’s not required.

Children and special cases

Kids don’t get the same tablet dose as adults. Instead, the drug is usually given as a liquid (suspension) measured in milligrams per kilogram of body weight. The typical schedule is 10 mg/kg on day 1, then 5 mg/kg once daily for the next four days.

If your child weighs less than 15 kg, the doctor might adjust the dose to keep the total amount under 500 mg. Always use the dosing syringe that comes with the medicine – a kitchen spoon can give the wrong amount.

People with liver disease, kidney problems, or those taking certain heart medications (like warfarin) may need a lower dose or longer interval between pills. Your doctor will run the numbers and tell you exactly what to do.

Here are a few quick safety pointers:

  • Finish the full course, even if you feel better. Stopping early can let bacteria survive and become resistant.
  • If you miss a dose, take it as soon as you remember – unless it’s almost time for the next dose. In that case, skip the missed one; don’t double up.
  • Common side effects include mild nausea, diarrhea, or a temporary change in taste. If you get a rash, severe stomach pain, or trouble breathing, call a doctor right away.
  • Avoid alcohol while on azithromycin if you notice an upset stomach; it can make the symptoms worse.

Bottom line: the standard adult plan is 500 mg once, then 250 mg daily for four days. Kids follow a weight‑based schedule, and special health conditions may require tweaks. Stick to the prescribed regimen, watch for side effects, and you’ll get the most out of your antibiotic without unnecessary hassle.

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