Narrow therapeutic index drugs require tighter bioequivalence standards to ensure patient safety. Learn how the FDA, EMA, and Health Canada regulate generics like warfarin, levothyroxine, and digoxin - and why even small differences matter.
Medical society guidelines on generic drug use vary by specialty. While most generics are safe, drugs with narrow therapeutic indices require caution. Learn which conditions demand careful substitution and why doctors sometimes oppose automatic swaps.